منابع مشابه
Treatment of acute migraine with subcutaneous sumatriptan.
Sumatriptan succinate, a 5-HT1D receptor agonist, constricts human cranial arteries. Two parallel-group trials for treatment of acute migraines were conducted in the United States. Adult patients were randomized and given either 6 mg of sumatriptan succinate subcutaneously (n = 734) or placebo (n = 370). At 1 hour, sumatriptan was significantly more effective than placebo in reducing moderate o...
متن کاملSumatriptan iontophoretic patch for migraine.
Sumatriptan delivered in an electric patch form applied to the skin was approved by the Federal Drug Administration (FDA) in 2013 for the acute treatment of migraine. About 25 years ago, sumatriptan was the first drug in the medication class of triptans to be approved for the treatment of migraine. Sumatriptan already comes in a tablet, injectable form, nasal spray, and in at least 14 countries...
متن کاملChanges in resource use and outcomes for patients with migraine treated with sumatriptan: a managed care perspective.
BACKGROUND Migraine headaches result in significant patient suffering and high costs to managed care organizations and employers. Studies that evaluate patient outcomes and the financial consequences of migraine treatment are important from a clinical and an economic perspective. METHODS This prospective, observational study assessed the outcomes of migraineurs in a mixed model staff/ indepen...
متن کاملIntranasal sumatriptan for migraine in children.
QUESTION I am seeing more and more children and adolescents with headaches that can be defined as migraine headache. I have read about intranasal sumatriptan as an abortive therapy. Is this an effective treatment? ANSWER Acute migraine headache among children and adolescents is common and treatment is challenging. Intranasal sumatriptan is a safe and mostly effective option for children and a...
متن کاملIntranasal sumatriptan study with high placebo response in Taiwanese patients with migraine.
BACKGROUND Triptan's efficacy in the treatment of migraine has never been reported in Taiwanese. A high placebo effect was reported in Japanese. The objective of this study was to evaluate the efficacy of intranasal sumatriptan in the acute treatment of migraine in Taiwanese patients. METHODS Fifty-eight patients who had experienced migraine for at least 1 year were randomly assigned to 2 gro...
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ژورنال
عنوان ژورنال: Mayo Clinic Proceedings
سال: 2002
ISSN: 0025-6196
DOI: 10.4065/77.2.201